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Do You Know How CBD Will React To Your Other Medications?

Run a quick Google search for “CBD Pills” and you’ll be bombarded by results. Products, articles, videos, and more will all be presented to you en mass, all presenting a different take on this promising compound. 

And we get it. The excitement behind CBD is obvious. We’ve all heard the success stories of some individuals using it to treat their epilepsy, and others using it as a health supplement to help them reach other health and wellness goals. But in many cases, these articles and anecdotes don’t often explore whether these individuals were using other drugs and medications as well.

Here at Axis Labs, we’re big fans of the basics of health. With proper diet and exercise, a good relationship with your doctor, plus adding in some CBD, you can live your best life. But we also believe that you should make educated decisions about health. While talking to your doctor about CBD, they might discuss how this cannabis compound can interact with your prescription or over-the-counter medications. Let’s take a quick look at this.

Using Just CBD

If you've read any of our articles in the past, or if you’ve caught up on other posts and videos, you’ll know that many are using CBD to help treat or manage a myriad of concerns. From workout recovery to testosterone, CBD can be used in a wide variety of ways. And when CBD products like pain relief creams and drops are used on their own, they’re basically benign. 

One of the reasons that many choose to use CBD instead of a pharmaceutical is that there are limited side effects and no risk of overdosing. While taking too much cannabidiol might result in minute concerns like grogginess or diarrhea, it’s nothing as severe as taking too much of an opioid or NSAID pain killer. Indeed, as one 2018 study found, you can take up to 1,500mg of CBD with no negative effects. The study had participants take nearly 30 times the recommended dosage of a specific CBD product, and none of them displayed anything more than mild symptoms. 

So when used alone, you can trust that CBD is safe, and could help you enhance your health and assist with a number of concerns you might have. From sleeplessness to chronic pain, to anxiety, and more, CBD can be a regular part of your health and wellness routine.

CBD and Your Medications

It’s when we start to use CBD with other medications and drugs that things start to get complicated. But before your eyes glaze over, bear with us, as this is pretty important stuff.

In some cases, there’s a chance that using cannabidiol could actually block the effects of your other medications. This can be challenging in some cases, and dire in others. But chemical interactions aren’t unexpected, because any medicines and supplements will interact with each other in some way. But what leads to these interactions?

CBD, the ECS, and Cytochrome P450

The reason that CBD has any effect on your body is because of your ECS, or endocannabinoid system. This is a network of receptors that runs throughout your body and is connected to your central nervous system. Not only that, your ECS is actually designed to absorb and use compounds like CBD.

But sometimes when your ECS absorbs CBD, it can interrupt other processes in your body, like the metabolizing processes of the liver enzyme cytochrome P450. In some cases, CBD could deactivate the CYP450 in your liver. This hampers your capability to metabolize the drugs and medications you might need to stay healthy. This makes these drugs far less effective or keeps them lingering in your system for a longer period of time. In either case, when a medication isn’t fully metabolized, your body could respond negatively, the drug could accrue in your bloodstream, and you might experience a more pressing health concern than the one you were trying to treat with the drug.

So Which Medications Don’t Get Along with CBD?

Unfortunately, there’s no master list of drug interactions we can refer you to. That’s in part because CBD is still being researched by private groups, universities, and even the government. But that doesn’t mean that there isn’t any research on these topics. Some studies have found obvious interactions between a medication and CBD.

Sedatives and Sleep Aids

Some already use CBD as a way to help lull themselves to sleep, and when used with prescription medicines, there’s some research to suggest that the cannabis compound can exaggerate the drug’s effects. While researchers don’t have a firm grasp on how the two interact yet, some have found that taking a sleep aid and CBD can make it difficult to stay awake. It’s in your best interest to not take CBD while also taking prescription sleep aids.

Seizure Drugs

CBD has become one of the biggest names in treating epilepsy and seizures out there. In fact, it’s been used successfully for many years, and the FDA has even approved a CBD-based drug for use. There’s a body of evidence to suggest that CBD may be an effective anti-seizure treatment option even on its own. But it may not be as effective when used alongside other drugs. As noted above, CBD can slow the CYP450 enzyme, which as a study from 1992, can prevent the build-up of anti-epileptic medications like norclobazam and clobazam in the bloodstream. In some cases, this exacerbated the symptoms of the next seizure.

Diabetes Medications

There hasn’t been a lot of research into the connection between CBD and diabetes, but what little there is quite promising. The evidence argues that CBD could help lower insulin resistance while also helping to bolster things like the metabolic process and control of blood sugars. Of course, there’s little research that has looked directly at how CBD and insulin interact.

Opioids

As part of the debate around the overuse of opioids, many have suggested that cannabis products like CBD be used as an alternative. The thinking is sound, as both opioids and CBD are used to help manage pain. 

Studies note that CBD could be used as an effective pain-reliever and even replacement for opioids. In 2011, a group of researchers asked subjects to use a vaporized CBD product alongside their regular opioid prescriptions. The study found that the concentration of opioids in the subjects’ blood levels weren’t changed at all by the use of cannabis. But, the subjects noted that they felt less pain after using the CBD.

How Do You Use CBD and Your Medications Together?

We’ve said it once, and we’ll say it again. When it comes to CBD, it’s best to take it low and take it slow. Everyone processes CBD differently, much in the same way that they metabolize medication differently. In reviewing the research, it has been found that, when taken in low-doses, CBD doesn’t have a pronounced effect on any doctor-prescribed medications. In other cases, there’s no effect at all. 

That said, it’s always a good idea to talk to your doctor about your use of CBD while you’re also taking other prescribed or over-the-counter medications. This is the best way to ensure that you stay safe and healthy, while also enjoying the maximum benefits of your medications and cannabis products. 

If you’re interested in switching to a healthy routine that makes great use of CBD, you can talk to your doctor about phasing out other medications in favor of CBD over time. 

Order Premium CBD Products Today

Lab-tested and quality-proven, all of the CBD products offered by Axis Labs are made from high-quality, Colorado-grown hemp, and are tested by a third-party to check for purity and potency. From CBD shots to gummies, tinctures for you and your pets, to pain relief creams, we have the right products for your lifestyle. Browse our collection and order yours today!

The Balance Between Diet and CBD

The Balance Between Diet and CBD

Perhaps now more than ever, people are aware of the effect their diet has on their overall sense of wellbeing. As a result, people are making more careful decisions about their dietary choices, eschewing things like cheap fast food in favor of “super” foods like kale, quinoa, and supporting supplements. Popular diet trends, like the ketogenic diet, have exploded into the popular consciousness because of their effectiveness.

Riding alongside the growing wave of dietary consciousness is the expanding popularity of cannabidiol or CBD. Praised for its myriad uses, CBD and other hemp-based products are being added to more and more products and lifestyles. It’s only natural then that people would be curious about the effects that CBD can have on your dieting efforts. 

Here at Axis Labs, we’re all about helping you live a happier and healthier life. It’s why we offer premium CBD and nutrition supplements. So let’s take a look at how CBD impacts your dieting strategies.

Hemp in the Human Diet

First, it’s important to recognize that the hemp plant itself has been a part of the human diet probably since the first time that humans cultivated the plant in any meaningful way. The seeds of the hemp plant can be eaten on their own or pressed to create an oil. It’s not uncommon to find hemp being added to more and more meals as the plant grows in popularity.

Adding CBD to your diet then doesn’t seem like as much of a stretch.

Yes, CBD Has Calories

Of course, a major part of any diet plan is the management of calories. While we might not think that CBD has a calorie count, it actually does. That’s because even products like CBD extracts are made with carrier agents from oils like MCT or coconut. Even hemp-based oils are rich in calories. It’s estimated that hemp oil has about 126 calories and 14g of fat in every tablespoon. But it’s rare that you’ll be consuming that much CBD in one go.

If you’re concerned about the calorie count of your CBD products, don’t panic. We’ve listed these calories on the back of each of our packages so you can find the right product to meet your calorie and dietary needs.

CBD and Your Favorite Drinks

For some CBD connoisseurs, taking CBD products on their own isn’t always appealing. Some complain of the distinct earthy taste of the hemp-derived compound, and so products like a CBD tincture might be difficult to enjoy on its own. Fortunately, CBD can be readily added to a wide variety of foods and drinks. 

CBD infused beverages are becoming a common sight at coffee shops, bars, and breweries across the country. That’s because everyone from coffee to beer snobs is enjoying some of the benefits that the cannabis compound has to offer.

For instance, when added to coffee, CBD can help you experience fewer jitters, those post-coffee cramps, and lessen the feeling of caffeine headaches. At the same time, you might notice that the focus that coffee offers you is enhanced by the presence of the CBD. You might feel more stable as well. When enjoyed in low doses, CBD can actually work as a stimulant, which can heighten the effects of your morning cup of coffee.

CBD is Affected By Food

We all react differently to the food that we ingest. Our bodies do a better or worse job of processing these nutrients based on our unique nutritional needs and genetic makeup. But some research suggests that your reaction to CBD may also be impacted by the foods you eat.

A 2019 study published in Epilepsia studied how the bodies of the subjects absorbed CBD after a meal. Eight participants were divided into two groups. The first was asked to take their CBD product as soon as they woke up. They were asked to eat breakfast four hours later. The second group ate a heavy breakfast burrito just 30 minutes after taking their CBD dose. 

The study produced some interesting results. Through blood analysis, it found that food impacts the body’s ability to absorb CBD. Researchers found that the participants would absorb four times as much CBD when they ate quickly after taking CBD. Ultimately, the study argued that CBD could be taken with food to help maximize the effects of the compound.

So How Do You Include CBD in Your Diet?

We know that CBD can be added to our food and drink and that doing so can actually amplify its effects, so how do we do it? One of the reasons CBD has become so popular is because of its flexibility. From gummy bears to bacon-flavored drops, CBD can be added to seemingly anything, so adding it to your next culinary creation seems like an obvious choice.

You can add CBD to nearly any dish, just keep a few tips in mind.

CBD is heat sensitive. That means that temperatures over 320 degrees Fahrenheit can begin to break down some of the active components within the compound. Also, CBD can begin to evaporate between 320 and 350 degrees. This means that CBD might not be great for your next open flame BBQ.

A little goes a long way when it comes to CBD. Make sure you add just a little CBD to your dish when you first start experimenting. Too much and you might experience a pronounced earthy, or in some cases, bitter, taste in your meal. Just like figuring out your particular dose of CBD, you can slowly add more to your meals over time.

CBD is a great source of essential fatty acids, and by using fats in your meals, you can help increase the bioavailability of the compound. Try mixing your CBD with products like oils or butter. 

CBD goes really well with sweet and savory flavors (which is why it tastes great in our gummies and Pina Colada shots). This makes it great for things like sauces, dressings, and soups. You can even drizzle your CBD oils over a meal so it serves as its own dressing.

Make CBD Part of Your Life Today

CBD has a lot to offer you. More than just a simple gummy treat or topical, it can be added to your favorite meals to add a fresh twist. When you’re ready to make CBD a part of your regular diet or health and wellness routine, make sure to try the top-shelf quality products from Axis Labs. Sourced from hemp grown at organic farms, we subject all of our products to a rigorous battery of third-party lab tests to ensure that our CBD meets our purity and potency standards

Check out our complete line up of CBD products and order yours today!

How to Microdose CBD

How to Microdose CBD

If you’ve paid attention to the news at all in the last year or so, you’ve no doubt heard about microdosing in one form or another. Commonly associated with illegal substances, like acid or psilocybin, the practice is to take small amounts of a substance throughout the day in order to sustain an effect.

But microdosing isn’t just for illegal substances and is actually a great fit for legal products like CBD. In fact, microdosing CBD might enhance its effects and help you get more out of each product. Not sure how to follow a microdosing strategy for your CBD? We’ve got your back. Axis Labs has assembled this brief guide to show you how!

Understanding Microdosing

It can be argued that the first time microdosing was tried was also the first time anyone tried LSD. Chemist Dr. Albert Hofmann created the substance and took minute amounts of it throughout the day for the last 20 years of his life. Hofmann discovered, and was later backed up by other researchers, that by taking small doses of a product throughout the day, he could manipulate the receptors in his body and achieve a certain effect by using less of the product.

How to Microdose

Microdosing can be accomplished in a number of ways. In fact, you can microdose with any of the CBD products we sell.

Some CBD products are better for microdosing than others. For instance, CBD oils and tinctures are taken using a dropper, which helps you take a precise amount of the oil. Softgels and capsules are filled with a fixed amount of CBD, meaning that you can predictably get the same amount of CBD each time you take it.

How effective the microdose will be is dependant on the bioavailability of that particular hemp-based product. For instance, taking CBD orally by ingesting something like a gummy means that the CBD has to be dissolved in the stomach before it can enter the bloodstream. This means that CBD gummies have a low level of bioavailability. On the other hand, sublingual CBD, like an oil, has a much higher level of bioavailability. Vaping has perhaps the highest level of bioavailability, as it interacts with the blood vessels lining your lungs almost immediately.

Once you’ve chosen the form of CBD you want to microdose, you can begin the process. Remember, everyone reacts differently to CBD, so how much you take will depend on your unique physiology and reaction the cannabis compound. Examine your usual dose of CBD and think about how you can spread that out over the course of a day. For instance, you might use 25mg of CBD each morning through a tincture. Instead, consider taking 5mg in the morning, 5 when you get to work, 5 more at lunch, another 5 at dinner, then the final 5 before bed. This could help you feel the effects throughout the day.

Microdosing for Beginners

Just like finding your ideal dosage of CBD, discovering the right amount of CBD to take in a microdose takes a little bit of experimentation and research. If you read this past blog, this process might seem familiar but it’s a little different.

Start with a small dosage. Something like 1mg. Over the next hour, record how you feel. If you don’t feel anything, take another dose of the same amount an hour after you took the first dose. Again, record your experiences. Try this amount of CBD at this same interval for a day. If you don’t feel anything, try a slightly larger amount the following day. Once you have a sense of how many milligrams you need to take and how often to get the desired effect, you can start to microdose with that throughout the day.

The Advantages of Microdosing CBD

By taking small doses of CBD throughout the day, you’re stimulating your Endocannabinoid on a regular basis. This means that the effects of the cannabis are constantly being experienced. For some, microdosing might become their preferred method of using CBD. That’s because it does a good job of keeping a balanced level of CBD in your system.

For those who use CBD for recurring or chronic concerns like generalized anxiety, pain, or depression, having a relatively constant amount of CBD in your body at any given moment may help you feel better than taking a larger dose at the beginning or end of your day.

Enhance Your Health Today

Ready to start microdosing? Then Axis Labs has the CBD products for you. Made from high-quality, industrial hemp, we work with a third-party lab to verify the purity and potency of all of our CBD and hemp oil products. From oils to gummies and much more, we’ve got the CBD that fits naturally into your lifestyle. Shop now!

Breaking Down Bioavailability and CBD

As a leading provider of hemp-based products like CBD, we get a lot of different questions from our customers. Things like “how do you test for purity?” and “can you travel with CBD?” are common questions, but another we get pretty regularly is “how long does it take for CBD to take effect?”

Well, like all good answers, it depends. There’s a lot that goes into how your body reacts to CBD, but a large part of that reaction is determined by the product itself. That’s because different CBD products have different levels of bioavailability. Don’t know what that means? Don’t worry, let Axis Labs break it down for you.

What Is Bioavailability?

Whenever you ingest or use a compound or substance, a certain amount of that eventually enters into your bloodstream. The amount of the compound that enters the bloodstream is bioavailable. Some compounds are more bioavailable than others, and that affects how much of it is absorbed. When it comes to CBD, there are four typical ways to use CBD and give it the chance to absorb into your bloodstream: inhalation, ingestion, and application. Each of these methods will play a part in how long your body takes to react to CBD.

Which CBD Product has the Most Bioavailability?

When you are looking to enjoy the effects of CBD right away, you have to think about how you’re administering the compound. Different products can be enjoyed in different ways, so let’s take a look at some of the most common products and their bioavailability.

Inhaling CBD

Studies generally suggest that the fastest way to introduce cannabidiol into your bloodstream is to inhale it. CBD can be inhaled in a variety of ways. Some manufacturers offer a distinct CBD e-liquid for your vaporizers, while others encourage you to make your own e-liquid using a CBD tincture as a base.

By inhaling CBD, you’re exposing the alveoli in your lungs to the compound. Your lungs are essentially one large surface to absorb the CBD and can almost immediately let it into your bloodstream. Not only that, but you can absorb more CBD through inhalation that you can other methods. Those who inhale CBD have offered anecdotal evidence that they feel the effects in as little as 15 minutes.

Ingesting CBD

There are lots of ways to ingest CBD. From tinctures to gummies to capsules and even pina colada flavored shots, you can take CBD sublingually or by eating it. While this is convenient, and you’re often getting a more precise dosage of CBD, it takes far longer to take effect.

That’s because the CBD has to be processed by your digestive system. More than just the stomach, other important organs like your liver have to process the CBD as well. The compound oxidizes certain enzymes in the liver, which can limit the amount of CBD that’s allowed to enter into the bloodstream. Those who ingest CBD have reported that it takes around two hours before they experience the effects.

Applying CBD

When it comes to applying CBD to the skin, the speed at which it takes effect is variable. That’s many CBD topicals and pain relief creams use a lipid or oily base that helps to transfer the CBD across the cell membrane and into your bloodstream.

CBD topicals are popular with those who have chronic aches and pains in their joints and muscles because it offers targeted pain relief. The problem, however, is that it can take a long time to take effect. Some find relief in just 30 minutes, while others only feel the effects of the CBD cream a day later. Some suggest that applying the topical frequently can accelerate the effects.

But is Faster Absorption Better?

Once again, it depends. CBD can be used for an ever-expanding list of reasons and different purposes. While those with chronic pain or sudden anxiety, it might be necessary to have a fast- acting way to enjoy CBD. For those individuals, they may need something like a CBD-based vape liquid. For others who are struggling with sleep or just need a little help to focus, a product with less bioavailability like CBD capsules might make more sense. Think about your needs and choose your products accordingly.

Hemp Extracts and CBD for Your Lifestyle

Axis Labs offers a wide array of CBD products all designed to fit into your lifestyle. With topicals, capsules, tinctures, gummies, and more, we’re sure you’ll find the right CBD product for you. Take a look at our catalog today and order yours!

 

What You Need to Know About Mislabeled CBD Products

CBD is becoming more popular by the day. Now that more and more people are beginning to recognize the benefits it has to offer, it seems like everyone is giving it a try. To meet the increasing demand for CBD products, dozens of fly-by-night manufacturers have sprouted up and have started offering less-than-quality CBD products. These sub-par products have earned a lot of attention — and not in a good way. In 2017, Penn Medicine at the University of Pennsylvania conducted a sprawling survey of CBD and hemp-based products. The results were shocking, to say the least. An estimated 70% of all CBD products are mislabeled in some way.

But what does this mean for you? As a purveyor of some of the purest and most potent lab-tested CBD products available, Axis Labs is here to outline this issue so you can make more informed purchasing decisions.

The Research into Quality CBD

There’s no denying that hemp and cannabidiol products are still an emerging field. Even the biggest and most well-known players are only a few years old. But in that time there has been a flurry of research into CBD and its effects. In response to the flood of products hitting the market recently, a few different research groups began examining whether CBD products like pills and tinctures were being labeled correctly.

The largest of these studies was undoubtedly the Penn Medicine report, but it was far from the only one. The Veterans Affairs office in San Diego, Americans for Safe Access, RTI International, John Hopkins, and Palo Alto University have all performed their own studies examining the same things.

In total, the studies would examine 84 hemp-based products and their advertised CBD concentrations. Ultimately, 26% contained less CBD than advertised, and 43% contained more. This means that many manufacturers are inconsistent in how they measure their concentrations and then advertise them. Interestingly, however, there were variations in the accuracy between products. For instance, 45% of CBD oils featured an accurate label, while only 12.5% of e-liquids for vapes were labeled correctly.

Understanding What These Studies Mean by “Mislabeled”

When these studies said that the products were “mislabeled,” it was more complicated than simply saying one product had CBD and another didn’t. Instead, the studies proposed two categories for mislabeled products: under and over-labeled products.

When a product is determined to be under-labeled, it means that the concentration of CBD in the product is higher than what’s advertised. Conversely, over-labeling means that the CBD concentration is lower than advertised. Troublingly, these studies found that only about a third of all of the CBD products tested had a concentration that was within 10% of what was advertised.

If it’s Not CBD, What is It?

While the discrepancies in CBD concentrations is concerning, even more concerning are other claims made on the packaging that may not be accurate. For instance, many CBD products are listed as having 0% THC concentration. Unfortunately, THC was more common in the CBD test products than is comfortable. THC was found in 21% of the products. Tetrahydrocannabinol is the psychoactive compound that gets some people “stoned,” and is a Schedule 1 drug at the federal level. This means that those who unknowingly purchase a hemp-based product with THC in it could face legal trouble.

As if the legal issues of THC in CBD products weren’t troubling enough, there are also health concerns. If the product is improperly labeled and it does contain THC, some users may unwittingly experience negative side effects as a result of ingesting the psychoactive compound. For parents who offer their children CBD as a way to help with seizures, the presence of THC can lead to distressing results for their children. In any case, CBD products are meant to help people, and the presence of THC or inaccurate concentrations may have a negative impact on the user’s health.

Why are Products Being Mislabeled?

Identifying which products are mislabeled is becoming easier, but figuring out why they’re being mislabeled in the first place is much harder. There is any number of factors that could lead to a mislabeled CBD product making it onto the market.

The availability of CBD and the complicated relationships it has with governments at the state and federal level plays a role. While CBD is legal for purchase in some states, it isn’t in others. Similarly, the DEA still considers it a Schedule 1 drug, despite the passage of critical legislature like the 2014 and 2018 Farm Bills.

Another issue is the expanding CBD market. As more and more companies bring products out, there is increased competition and tighter margins for success. Companies may cut corners in order to meet sales goals and quotas.

Finally, there’s the lack of clear government oversight and regulation of hemp-derived products like CBD. Researchers in the Penn Medicine study made the case that without clear FDA regulations, CBD will continue to be mislabeled. That’s because there are no clear ways to produce, test, and label CBD products in an accurate way.

How Axis Labs Tests for Accuracy

However, not all CBD manufacturers are producing mislabeled products. In lieu of government regulations, leading CBD brands like Axis Labs are choosing to test their own products for purity and potency. In our case, we have partnered with a hemp and CBD testing facility called Botanacor.

This lab works with all hemp-derived products and we submit a sample of every one of our products to their lab for testing. Their team starts by checking for the presence of THC in the product before measuring the potency of our CBD products by using an HPLC method paired with spectral analysis. To ensure that we’re offering the purest CBD available, our sample products are submitted for a solvent analysis to make sure that there are no byproducts from the extraction process. Finally, we request that our CBD products are run through a microbial contaminant test to check for undesirable things like yeasts and molds.

Why is Third-Party Lab Testing Important?

While third-party lab testing isn’t a requirement to bring a CBD product onto the market, it’s in the best interest of the manufacturer to do so. This ensures that their products can legitimately command the prices that they do and that they are safe for consumers to use. Indeed, the presence of a third-party testing label on CBD products actually serves as a selling point and it’s why we choose to share all of our lab test results right on our website.

Order Your Premium CBD Pills Today

If you don’t want to play the guessing game of which CBD pills and tinctures are labeled correctly, then the easiest step to take is to simply order all your CBD from Axis Labs. Derived from a high-quality industrial grown hemp, you can trust us to offer you the CBD pills, gummies, creams, and tinctures you need to enhance your lifestyle. Order your CBD today.